1jgn

Solution NMR

Solution structure of the C-terminal PABC domain of human poly(A)-binding protein in complex with the peptide from Paip2

Released:

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Polyadenylate-binding protein 1 Chain: A
Molecule details ›
Chain: A
Length: 98 amino acids
Theoretical weight: 10.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P11940 (Residues: 544-636; Coverage: 15%)
Gene names: PAB1, PABP1, PABPC1, PABPC2
Sequence domains: Poly-adenylate binding protein, unique domain
Structure domains: c-terminal domain of poly(a) binding protein
Polyadenylate-binding protein-interacting protein 2 Chain: B
Molecule details ›
Chain: B
Length: 22 amino acids
Theoretical weight: 2.39 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9BPZ3 (Residues: 106-127; Coverage: 17%)
Gene names: HSPC218, PAIP2, PAIP2A
Sequence domains: Ataxin-2 C-terminal region

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 68%
Refinement method: simulated annealing
Expression system: Escherichia coli