1jgl

X-ray diffraction
2.15Å resolution

Crystal structure of immunoglobulin Fab fragment complexed with 17-beta-estradiol

Released:
Source organism: Mus musculus

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Anti-colorectal carcinoma light chain Chain: L
Molecule details ›
Chain: L
Length: 214 amino acids
Theoretical weight: 23.67 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q7TS98 (Residues: 23-236; Coverage: 100%)
Sequence domains:
Structure domains: Immunoglobulins
Ig gamma-1-chain Chain: H
Molecule details ›
Chain: H
Length: 218 amino acids
Theoretical weight: 23.46 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200HB
Spacegroup: P212121
Unit cell:
a: 48.207Å b: 64.496Å c: 165.285Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.199 0.199 0.249
Expression system: Escherichia coli