Function and Biology Details
Reactions catalysed:
Purine deoxynucleoside + phosphate = purine + 2'-deoxy-alpha-D-ribose 1-phosphate
S-methyl-5'-thioadenosine + phosphate = adenine + S-methyl-5-thio-alpha-D-ribose 1-phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
homo hexamer (preferred)
Assembly name:
Purine nucleoside phosphorylase (preferred)
PDBe Complex ID:
PDB-CPX-156172 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Purine nucleoside phosphorylase
Molecule details ›
Chains: A, B, C
Length: 236 amino acids
Theoretical weight: 25.76 KDa
Source organism: Saccharolobus solfataricus
Expression system: Escherichia coli
UniProt:
Sequence domains: Phosphorylase superfamily
Structure domains: Nucleoside phosphorylase domain
Length: 236 amino acids
Theoretical weight: 25.76 KDa
Source organism: Saccharolobus solfataricus
Expression system: Escherichia coli
UniProt:
- Canonical:
P50389 (Residues: 1-236; Coverage: 100%)
Sequence domains: Phosphorylase superfamily
Structure domains: Nucleoside phosphorylase domain
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
NSLS BEAMLINE X12C
Spacegroup:
C2221
Expression system: Escherichia coli
