› 1jaj

Solution NMR

Solution Structure of DNA Polymerase X from the African Swine Fever Virus

Released:
DOI: 10.2210/pdb1jaj/pdb
PDB entry 1jaj coloured by chain, ensemble of 25 models, front view.
PDB entry 1jaj coloured by chain, ensemble of 25 models, side view.
PDB entry 1jaj coloured by chain, ensemble of 25 models, top view.
Source organism: African swine fever virus BA71V
Primary publication:
Solution structure of a viral DNA repair polymerase.
Maciejewski MW, Shin R, Pan B, Marintchev A, Denninger A, Mullen MA, Chen K, Gryk MR, Mullen GP
Nat Struct Biol 8 936-41 (2001)
PMID: 11685238

Function and Biology Details

Reaction catalysed: 
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-154656 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Repair DNA polymerase X Chain: A
Molecule details ›
Chain: A
Length: 174 amino acids
Theoretical weight: 20.35 KDa
Source organism: African swine fever virus BA71V
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P42494 (Residues: 1-174; Coverage: 100%)
Gene names: Ba71V-97, O174L
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 84%
Refinement method: torsion angle dynamics energy minimization
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

4 review citations

The DNA-polymerase-X family: controllers of DNA quality?
Ramadan et al. (2004)
3 more

6 mentions without citation

A widespread bacteriophage abortive infection system functions through a Type IV toxin-antitoxin mechanism.
Dy et al. (2014)
5 more