X-ray diffraction
2.1Å resolution

Function and Biology Details

Reaction catalysed:
S-(5-deoxy-D-ribos-5-yl)-L-homocysteine = L-homocysteine + (4S)-4,5-dihydroxypentan-2,3-dione
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
S-ribosylhomocysteine lyase Chains: A, B
Molecule details ›
Chains: A, B
Length: 175 amino acids
Theoretical weight: 19.85 KDa
Source organism: Haemophilus influenzae
Expression system: Escherichia coli
  • Canonical: P44007 (Residues: 2-167; Coverage: 99%)
Gene names: HI_0491, luxS
Sequence domains: S-Ribosylhomocysteinase (LuxS)
Structure domains: S-ribosylhomocysteinase (LuxS)

Ligands and Environments

2 bound ligands:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 32-ID
Spacegroup: P42212
Unit cell:
a: 129.669Å b: 129.669Å c: 53.77Å
α: 90° β: 90° γ: 90°
R R work R free
0.215 0.213 0.238
Expression system: Escherichia coli