X-ray diffraction
2.18Å resolution

Crystal structure of Thermococcus litoralis phosphogrucose isomerase complexed with gluconate-6-phosphate

Source organism: Thermococcus litoralis
Entry authors: Jeong J-J, Fushinobu S, Ito S, Hidaka M, Shoun H, Wakagi T

Function and Biology Details

Reaction catalysed:
Alpha-D-glucose 6-phosphate = beta-D-fructofuranose 6-phosphate
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Glucose-6-phosphate isomerase Chains: A, B
Molecule details ›
Chains: A, B
Length: 190 amino acids
Theoretical weight: 21.75 KDa
Source organism: Thermococcus litoralis
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P84140 (Residues: 1-190; Coverage: 100%)
Gene name: pgiA
Sequence domains: Glucose-6-phosphate isomerase (GPI)
Structure domains: Jelly Rolls

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU ULTRAX 18
Spacegroup: P212121
Unit cell:
a: 40.67Å b: 80.23Å c: 130.04Å
α: 90° β: 90° γ: 90°
R R work R free
0.22 0.218 0.263
Expression system: Escherichia coli BL21(DE3)