Function and Biology

Crystal structure of archaeal XPF/Mus81 homolog, Hef from Pyrococcus furiosus, nuclease domain, Ca cocrystal

Source organism: Pyrococcus furiosus DSM 3638
Biochemical function: nuclease activity
Biological process: not assigned
Cellular component: not assigned

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF02732
Domain description: ERCC4 domain
Occurring in:
  1. ATP-dependent RNA helicase, putative
The deposited structure of PDB entry 1j24 contains 1 copy of Pfam domain PF02732 (ERCC4 domain) in ATP-dependent RNA helicase, putative. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR006166
Domain description: ERCC4 domain
Occurring in:
  1. ATP-dependent RNA helicase, putative
IPR011335
Domain description: Restriction endonuclease type II-like
Occurring in:
  1. ATP-dependent RNA helicase, putative

Structure domain

CATH CATH domain
3.40.50.10130
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: Rossmann fold
Occurring in:
  1. ATP-dependent RNA helicase, putative
The deposited structure of PDB entry 1j24 contains 1 copy of CATH domain 3.40.50.10130 (Rossmann fold) in ATP-dependent RNA helicase, putative. Showing 1 copy in chain A.
SCOP SCOP annotation
89716
Class: Alpha and beta proteins (a/b)
Fold: Restriction endonuclease-like
Superfamily: Restriction endonuclease-like
Occurring in:
  1. ATP-dependent RNA helicase, putative
The deposited structure of PDB entry 1j24 contains 1 copy of SCOP domain 89716 (XPF/Rad1/Mus81 nuclease) in ATP-dependent RNA helicase, putative. Showing 1 copy in chain A.