1iv6

Solution NMR

Solution Structure of the DNA Complex of Human TRF1

Released:
Source organism: Homo sapiens

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
1 distinct polypeptide molecule
2 distinct DNA molecules
Macromolecules (3 distinct):
Telomeric repeat-binding factor 1 Chain: A
Molecule details ›
Chain: A
Length: 70 amino acids
Theoretical weight: 8.6 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P54274 (Residues: 370-439; Coverage: 16%)
Gene names: PIN2, TERF1, TRBF1, TRF, TRF1
Sequence domains: Myb-like DNA-binding domain
Structure domains: Homeodomain-like
5'-D(*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3' Chain: B
Molecule details ›
Chain: B
Length: 13 nucleotides
Theoretical weight: 4.1 KDa
Source organism: Homo sapiens
Expression system: Not provided
5'-D(*CP*CP*CP*TP*AP*AP*CP*CP*CP*TP*AP*AP*C)-3' Chain: C
Molecule details ›
Chain: C
Length: 13 nucleotides
Theoretical weight: 3.84 KDa
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 56%
Refinement method: distance geometry/simulated annealing
Expression systems:
  • Escherichia coli
  • Not provided