Function and Biology Details
Reaction catalysed:
Endonucleolytic cleavage at a junction such as a reciprocal single-stranded crossover between two homologous DNA duplexes (Holliday junction)
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
Crossover junction endodeoxyribonuclease Hjc (preferred)
PDBe Complex ID:
PDB-CPX-123093 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Crossover junction endodeoxyribonuclease Hjc
Molecule details ›
Chains: A, B
Length: 123 amino acids
Theoretical weight: 13.79 KDa
Source organism: Pyrococcus furiosus
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Archaeal holliday junction resolvase (hjc)
Structure domains: Trna Endonuclease; Chain: A, domain 1
Length: 123 amino acids
Theoretical weight: 13.79 KDa
Source organism: Pyrococcus furiosus
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
E7FHX4 (Residues: 1-123; Coverage: 100%)
Sequence domains: Archaeal holliday junction resolvase (hjc)
Structure domains: Trna Endonuclease; Chain: A, domain 1
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SPRING-8 BEAMLINE BL24XU
Spacegroup:
P65
Expression system: Escherichia coli BL21(DE3)
