1igy

X-ray diffraction
3.2Å resolution

STRUCTURE OF IMMUNOGLOBULIN

Released:
Source organism: Mus musculus
Primary publication:
Crystallographic structure of an intact IgG1 monoclonal antibody.
J Mol Biol 275 861-72 (1998)
PMID: 9480774

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-134700 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (4 distinct):
Immunoglobulin kappa constant Chains: A, C
Molecule details ›
Chains: A, C
Length: 213 amino acids
Theoretical weight: 23.52 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P01837 (Residues: 1-107; Coverage: 100%)
Gene name: Igkc
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Ig gamma-1 chain C region, membrane-bound form Chains: B, D
Molecule details ›
Chains: B, D
Length: 434 amino acids
Theoretical weight: 47.91 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P01869 (Residues: 1-320; Coverage: 81%)
Gene names: Igh-4, Ighg1
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, NDG, BMA, MAN, GAL, FUL
Carbohydrate polymer : NEW Components: NAG, NDG, BMA, MAN, GAL, FUC
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12C
Spacegroup: P21
Unit cell:
a: 66.65Å b: 190.66Å c: 73.1Å
α: 90° β: 109.66° γ: 90°
R-values:
R R work R free
0.211 0.211 0.327