X-ray diffraction
1.8Å resolution

Crystal Structure of yeast Thiamin Pyrophosphokinase

Source organism: Saccharomyces cerevisiae
Primary publication:
The crystal structure of yeast thiamin pyrophosphokinase.
Structure 9 539-46 (2001)
PMID: 11435118

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Thiamine pyrophosphokinase Chains: A, B
Molecule details ›
Chains: A, B
Length: 319 amino acids
Theoretical weight: 36.66 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P35202 (Residues: 1-319; Coverage: 100%)
Gene names: THI80, YOR143C, YOR3373C
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P21212
Unit cell:
a: 118.313Å b: 130.839Å c: 44.319Å
α: 90° β: 90° γ: 90°
R R work R free
0.217 0.217 0.234
Expression system: Escherichia coli BL21(DE3)