› 1ich

Solution NMR

SOLUTION STRUCTURE OF THE TUMOR NECROSIS FACTOR RECEPTOR-1 DEATH DOMAIN

Released:
DOI: 10.2210/pdb1ich/pdb
PDB 1ich coloured by chain and viewed from the front.
PDB 1ich coloured by chain and viewed from the side.
PDB 1ich coloured by chain and viewed from the top.
Source organism: Homo sapiens
Primary publication:
Solution structure of the tumor necrosis factor receptor-1 death domain.
Sukits SF, Lin LL, Hsu S, Malakian K, Powers R, Xu GY
J. Mol. Biol. 310 895-906 (2001)
PMID: 11453696

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tumor necrosis factor receptor superfamily member 1A, membrane form Chain: A
Molecule details ›
Chain: A
Length: 112 amino acids
Theoretical weight: 12.81 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P19438 (Residues: 345-455; Coverage: 26%)
Gene names: TNFAR, TNFR1, TNFRSF1A
Sequence domains: Death domain
Structure domains: Death Domain, Fas

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: Distance geometry, Simulated annealing molecular dynamics
Chemical shifts: BMR5018  
Expression system: Escherichia coli

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Citations

8 review citations

Structural principles of tumor necrosis factor superfamily signaling.
Vanamee et al. (2018)
7 more

3 mentions without citation

Highly precise protein-protein interaction prediction based on consensus between template-based and de novo docking methods.
Ohue et al. (2013)
2 more