Structure analysis

RNA POLYMERASE II ELONGATION COMPLEX

X-ray diffraction
3.3Å resolution
Source organism: Saccharomyces cerevisiae
Assembly composition:
hetero dodecamer (preferred)
Entry contents: 10 distinct polypeptide molecules
1 distinct DNA molecule
1 distinct RNA molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero dodecamer
Accessible surface area: 141545.96 Å2
Buried surface area: 60290.08 Å2
Dissociation area: 1,611.83 Å2
Dissociation energy (ΔGdiss): 4.82 kcal/mol
Dissociation entropy (TΔSdiss): 11.24 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-113944

Macromolecules

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Chain: H
Length: 146 amino acids
Theoretical weight: 16.53 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P20436 (Residues: 1-146; Coverage: 100%)
Gene names: RPB8, YOR224C, YOR50-14
Pfam: RNA polymerase Rpb8
InterPro:
CATH: Nucleic acid-binding proteins
SCOP: RNA polymerase subunit RBP8

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Name: 5'-D(P*AP*AP*AP*TP*GP*CP*CP*TP*GP*GP*TP*CP*T)-3'
Representative chains: D
Length: 13 nucleotides
Theoretical weight: 3.97 KDa

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Name: 5'-R(P*GP*AP*CP*CP*AP*GP*GP*CP*A)-3'
Representative chains: R
Length: 9 nucleotides
Theoretical weight: 2.89 KDa

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