1hyl

X-ray diffraction
1.8Å resolution

THE 1.8 A STRUCTURE OF COLLAGENASE FROM HYPODERMA LINEATUM

Released:
Source organism: Hypoderma lineatum
Primary publication:
1.8 A structure of Hypoderma lineatum collagenase: a member of the serine proteinase family.
Acta Crystallogr. D Biol. Crystallogr. 52 380-92 (1996)
PMID: 15299709

Function and Biology Details

Reaction catalysed:
Hydrolysis of proteins including native collagen at -|-Ala bond leaving an N-terminal (75%) and a C-terminal (25%) fragment.
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Collagenase Chains: A, B
Molecule details ›
Chains: A, B
Length: 230 amino acids
Theoretical weight: 25.25 KDa
Source organism: Hypoderma lineatum
Expression system: Not provided
UniProt:
  • Canonical: P08897 (Residues: 31-260; Coverage: 94%)
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: I422
Unit cell:
a: 111.7Å b: 111.7Å c: 165.8Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.183 0.183 not available
Expression system: Not provided