Structure analysis

COMPLEX OF THE CATALYTIC PORTION OF HUMAN HMG-COA REDUCTASE WITH ATORVASTATIN

X-ray diffraction
2.22Å resolution
Source organism: Homo sapiens
Assembly composition:
homo tetramer (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Multimeric state: homo tetramer
Accessible surface area: 49500 Å2
Buried surface area: 30800 Å2
Dissociation area: 3,600 Å2
Dissociation energy (ΔGdiss): 63 kcal/mol
Dissociation entropy (TΔSdiss): 16 kcal/mol
Interface energy (ΔGint): -211 kcal/mol
Symmetry number: 4

Macromolecules

Search similar proteins