1huw

X-ray diffraction
2Å resolution

THE CRYSTAL STRUCTURE OF AFFINITY-MATURED HUMAN GROWTH HORMONE AT 2 ANGSTROMS RESOLUTION

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Somatotropin Chain: A
Molecule details ›
Chain: A
Length: 191 amino acids
Theoretical weight: 21.99 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P01241 (Residues: 27-217; Coverage: 100%)
Gene name: GH1
Structure domains: Growth Hormone; Chain: A;

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: C2
Unit cell:
a: 80.45Å b: 59.34Å c: 50.87Å
α: 90° β: 128.2° γ: 90°
R-values:
R R work R free
0.185 0.185 not available
Expression system: Not provided