1hso

X-ray diffraction
2.5Å resolution

HUMAN ALPHA ALCOHOL DEHYDROGENASE (ADH1A)

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alcohol dehydrogenase 1A Chains: A, B
Molecule details ›
Chains: A, B
Length: 374 amino acids
Theoretical weight: 39.78 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P07327 (Residues: 2-375; Coverage: 100%)
Gene names: ADH1, ADH1A
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand NAD 2 x NAD
2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P21
Unit cell:
a: 55.7Å b: 100.2Å c: 69.1Å
α: 90° β: 104.9° γ: 90°
R-values:
R R work R free
0.194 0.248 0.191
Expression system: Escherichia coli