› 1hq8

X-ray diffraction
1.95Å resolution

CRYSTAL STRUCTURE OF THE MURINE NK CELL-ACTIVATING RECEPTOR NKG2D AT 1.95 A

Released:
DOI: 10.2210/pdb1hq8/pdb
PDB entry 1hq8 coloured by chain, front view.
PDB entry 1hq8 coloured by chain, side view.
PDB entry 1hq8 coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Crystal structure of the murine NK cell-activating receptor NKG2D at 1.95 A.
Wolan DW, Teyton L, Rudolph MG, Villmow B, Bauer S, Busch DH, Wilson IA
Nat Immunol 2 248-54 (2001)
PMID: 11224525

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-129504 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
NKG2-D type II integral membrane protein Chain: A
Molecule details ›
Chain: A
Length: 123 amino acids
Theoretical weight: 14.11 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: O54709 (Residues: 110-232; Coverage: 53%)
Gene names: Klrk1, Nkg2d
Sequence domains: Lectin C-type domain
Structure domains: Mannose-Binding Protein A, subunit A

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: I212121
Unit cell:
a: 49.86Å b: 85.19Å c: 87.58Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.215 0.215 0.227
Expression system: Escherichia coli

Quick links

Citations

23 review citations

Roles of the NKG2D immunoreceptor and its ligands.
Raulet DH. (2003)
22 more

1 mention without citation

Structure of the fungal beta-glucan-binding immune receptor dectin-1: implications for function.
Brown et al. (2007)