1hl5

X-ray diffraction
1.8Å resolution

The Structure of Holo Type Human Cu, Zn Superoxide Dismutase

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Superoxide dismutase [Cu-Zn] Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, S
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, S
Length: 153 amino acids
Theoretical weight: 15.83 KDa
Source organism: Homo sapiens
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: P00441 (Residues: 2-154; Coverage: 99%)
Gene name: SOD1
Sequence domains: Copper/zinc superoxide dismutase (SODC)
Structure domains: Superoxide dismutase, copper/zinc binding domain

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX14.2
Spacegroup: P21
Unit cell:
a: 76.871Å b: 172.38Å c: 112.45Å
α: 90° β: 93.45° γ: 90°
R-values:
R R work R free
0.187 0.185 0.222
Expression system: Saccharomyces cerevisiae