X-ray diffraction
2.6Å resolution

mycobacterium diaminopimelate dicarboxylase (lysa)


Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Diaminopimelate decarboxylase Chains: A, B
Molecule details ›
Chains: A, B
Length: 453 amino acids
Theoretical weight: 48.34 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli
  • Canonical: P9WIU7 (Residues: 1-447; Coverage: 100%)
Gene names: MTCY373.13, Rv1293, lysA
Sequence domains:
Structure domains:

Ligands and Environments

Cofactor: Ligand PLP 2 x PLP
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 14-ID-B
Spacegroup: P41212
Unit cell:
a: 111.452Å b: 111.452Å c: 238.253Å
α: 90° β: 90° γ: 90°
R R work R free
0.227 0.224 0.268
Expression system: Escherichia coli