› 1hk6

Solution NMR

Ral binding domain from Sec5

Released:
DOI: 10.2210/pdb1hk6/pdb
PDB entry 1hk6 coloured by chain, ensemble of 25 models, front view.
PDB entry 1hk6 coloured by chain, ensemble of 25 models, side view.
PDB entry 1hk6 coloured by chain, ensemble of 25 models, top view.
Source organism: Mus musculus
Primary publication:
Structure of the GTPase-binding domain of Sec5 and elucidation of its Ral binding site.
Mott HR, Nietlispach D, Hopkins LJ, Mirey G, Camonis JH, Owen D
J Biol Chem 278 17053-9 (2003)
PMID: 12624092

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190051 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Exocyst complex component 2 Chain: A
Molecule details ›
Chain: A
Length: 95 amino acids
Theoretical weight: 10.11 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9D4H1 (Residues: 5-97; Coverage: 10%)
Gene names: Exoc2, Sec5, Sec5l1
Sequence domains: IPT/TIG domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

9 review citations

Tethering factors as organizers of intracellular vesicular traffic.
Yu et al. (2010)
8 more

2 mentions without citation

Structural basis of the interaction between RalA and Sec5, a subunit of the sec6/8 complex.
Fukai et al. (2003)
1 more