Function and Biology

The active N-terminal region of p67phox: Structure at 1.8 Angstrom resolution and biochemical characterizations of the A128V mutant implicated in chronic granulomatous disease

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF13181
Domain description: Tetratricopeptide repeat
Occurring in:
  1. Neutrophil cytosol factor 2
The deposited structure of PDB entry 1hh8 contains 1 copy of Pfam domain PF13181 (Tetratricopeptide repeat) in Neutrophil cytosol factor 2. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR019734
Domain description: Tetratricopeptide repeat
Occurring in:
  1. Neutrophil cytosol factor 2
IPR011990
Domain description: Tetratricopeptide-like helical domain superfamily
Occurring in:
  1. Neutrophil cytosol factor 2
IPR013105
Domain description: Tetratricopeptide repeat 2
Occurring in:
  1. Neutrophil cytosol factor 2

Structure domain

CATH CATH domain
1.25.40.10
Class: Mainly Alpha
Architecture: Alpha Horseshoe
Topology: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat
Homology: Tetratricopeptide repeat domain
Occurring in:
  1. Neutrophil cytosol factor 2
The deposited structure of PDB entry 1hh8 contains 1 copy of CATH domain 1.25.40.10 (Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat) in Neutrophil cytosol factor 2. Showing 1 copy in chain A.
SCOP SCOP annotation
48453
Class: All alpha proteins
Fold: alpha-alpha superhelix
Superfamily: TPR-like
Occurring in:
  1. Neutrophil cytosol factor 2
The deposited structure of PDB entry 1hh8 contains 1 copy of SCOP domain 48453 (Tetratricopeptide repeat (TPR)) in Neutrophil cytosol factor 2. Showing 1 copy in chain A.