Assemblies
Assembly Name:
All-trans-retinol dehydrogenase [NAD(+)] ADH1B
Multimeric state:
homo dimer
Accessible surface area:
26849.09 Å2
Buried surface area:
6915.03 Å2
Dissociation area:
1,706.44
Å2
Dissociation energy (ΔGdiss):
12.58
kcal/mol
Dissociation entropy (TΔSdiss):
14
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-132402
Macromolecules
Chains: A, B
Length: 374 amino acids
Theoretical weight: 39.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Pfam:
InterPro:
SCOP:
Length: 374 amino acids
Theoretical weight: 39.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P00325 (Residues: 2-375; Coverage: 100%)
Pfam:
InterPro:
- GroES-like superfamily
- Polyketide synthase, enoylreductase domain
- Alcohol dehydrogenase-like, N-terminal
- Alcohol dehydrogenase, zinc-type, conserved site
- NAD(P)-binding domain superfamily
- Alcohol dehydrogenase-like, C-terminal
SCOP:
![All-trans-retinol dehydrogenase [NAD(+)] ADH1B in PDB entry 1hdx, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/1hdx_entity_1_front_image-200x200.png "Homo dimeric assembly 1 of PDB entry <span class='highlight'>1hdx</span> contains 2 copies of <span class='highlight'>All-trans-retinol dehydrogenase [NAD(+)] ADH1B</span>. Front view.")
![All-trans-retinol dehydrogenase [NAD(+)] ADH1B in PDB entry 1hdx, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/1hdx_entity_1_side_image-200x200.png "Homo dimeric assembly 1 of PDB entry <span class='highlight'>1hdx</span> contains 2 copies of <span class='highlight'>All-trans-retinol dehydrogenase [NAD(+)] ADH1B</span>. Side view.")
![All-trans-retinol dehydrogenase [NAD(+)] ADH1B in PDB entry 1hdx, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/1hdx_entity_1_top_image-200x200.png "Homo dimeric assembly 1 of PDB entry <span class='highlight'>1hdx</span> contains 2 copies of <span class='highlight'>All-trans-retinol dehydrogenase [NAD(+)] ADH1B</span>. Top view.")