Function and Biology

HEREGULIN-ALPHA EPIDERMAL GROWTH FACTOR-LIKE DOMAIN, NMR, MINIMIZED AVERAGE STRUCTURE

Source organism: Homo sapiens
Biochemical function: signaling receptor binding
Biological process: nervous system development
Cellular component: not assigned

GO terms

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00008
Domain description: EGF-like domain
Occurring in:
  1. Neuregulin-1
1 copy of Pfam domain PF00008 (EGF-like domain) in Neuregulin-1 in PDB 1haf.

InterPro InterPro annotations
IPR000742
Domain description: EGF-like domain
Occurring in:
  1. Neuregulin-1
IPR040180
Domain description: Neuregulin
Occurring in:
  1. Neuregulin-1
IPR018250
Domain description: Neuregulin-1
Occurring in:
  1. Neuregulin-1

Structure domain

CATH CATH domain
2.10.25.10
Class: Mainly Beta
Architecture: Ribbon
Topology: Laminin
Homology: Laminin
Occurring in:
  1. Neuregulin-1
1 copy of CATH domain 2.10.25.10 (Laminin) in Neuregulin-1 in PDB 1haf.
SCOP SCOP annotation
57197
Class: Small proteins
Fold: Knottins (small inhibitors, toxins, lectins)
Superfamily: EGF/Laminin
Occurring in:
  1. Neuregulin-1
1 copy of SCOP domain 57197 (EGF-type module) in Neuregulin-1 in PDB 1haf.