› 1h9g

X-ray diffraction
2.1Å resolution

FadR, FATTY ACID RESPONSIVE TRANSCRIPTION FACTOR FROM E. COLI, in complex with myristoyl-CoA

Released:
DOI: 10.2210/pdb1h9g/pdb
PDB entry 1h9g coloured by chain, front view.
PDB entry 1h9g coloured by chain, side view.
PDB entry 1h9g coloured by chain, top view.
Source organism: Escherichia coli
Primary publication:
The structural basis of acyl coenzyme A-dependent regulation of the transcription factor FadR.
van Aalten DM, DiRusso CC, Knudsen J
EMBO J 20 2041-50 (2001)
PMID: 11296236

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fatty acid metabolism regulator protein Chain: A
Molecule details ›
Chain: A
Length: 243 amino acids
Theoretical weight: 27.49 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P0A8V6 (Residues: 1-239; Coverage: 100%)
Gene names: JW1176, b1187, fadR, oleR, thdB
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand COA 1 x COA
Ligand MYR 1 x MYR
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X11
Spacegroup: P6122
Unit cell:
a: 59.476Å b: 59.476Å c: 290.483Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.226 0.226 0.256
Expression system: Escherichia coli

Quick links

Citations

18 review citations

Bacterial transcriptional regulators for degradation pathways of aromatic compounds.
Tropel et al. (2004)
17 more

5 mentions without citation

The structural basis of acyl coenzyme A-dependent regulation of the transcription factor FadR.
van Aalten et al. (2001)
4 more