Function and Biology

Solution structure of the single-stranded DNA-binding Cold Shock Domain (CSD) of human Y-box protein 1 (YB1) determined by NMR (10 lowest energy structures)

Source organism: Homo sapiens
Biochemical function: nucleic acid binding
Biological process: not assigned
Cellular component: not assigned

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00313
Domain description: 'Cold-shock' DNA-binding domain
Occurring in:
  1. Y-box-binding protein 1
The deposited structure of PDB entry 1h95 contains 1 copy of Pfam domain PF00313 ('Cold-shock' DNA-binding domain) in Y-box-binding protein 1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR002059
Domain description: Cold-shock protein, DNA-binding
Occurring in:
  1. Y-box-binding protein 1
IPR012340
Domain description: Nucleic acid-binding, OB-fold
Occurring in:
  1. Y-box-binding protein 1
IPR019844
Domain description: Cold-shock (CSD) domain
Occurring in:
  1. Y-box-binding protein 1
IPR011129
Domain description: Cold shock domain
Occurring in:
  1. Y-box-binding protein 1
IPR012156
Domain description: Cold shock, CspA
Occurring in:
  1. Y-box-binding protein 1

Structure domain

CATH CATH domain
2.40.50.140
Class: Mainly Beta
Architecture: Beta Barrel
Topology: OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Homology: Nucleic acid-binding proteins
Occurring in:
  1. Y-box-binding protein 1
The deposited structure of PDB entry 1h95 contains 1 copy of CATH domain 2.40.50.140 (OB fold (Dihydrolipoamide Acetyltransferase, E2P)) in Y-box-binding protein 1. Showing 1 copy in chain A.
SCOP SCOP annotation
50282
Class: All beta proteins
Fold: OB-fold
Superfamily: Nucleic acid-binding proteins
Occurring in:
  1. Y-box-binding protein 1
The deposited structure of PDB entry 1h95 contains 1 copy of SCOP domain 50282 (Cold shock DNA-binding domain-like) in Y-box-binding protein 1. Showing 1 copy in chain A.