X-ray diffraction
1.8Å resolution

Crystal Structure of the Eosinophil Major Basic Protein at 1.8A: An Atypical Lectin with a Paradigm Shift in Specificity


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Eosinophil granule major basic protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 117 amino acids
Theoretical weight: 13.82 KDa
Source organism: Homo sapiens
  • Canonical: P13727 (Residues: 106-222; Coverage: 57%)
Gene names: MBP, PRG2
Sequence domains: Lectin C-type domain
Structure domains: Mannose-Binding Protein A, subunit A

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX14.1
Spacegroup: C2
Unit cell:
a: 74.328Å b: 57.487Å c: 60.961Å
α: 90° β: 113.2° γ: 90°
R R work R free
0.234 0.234 0.264