Function and Biology Details
Reactions catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Selective cleavage of Gln-|-Gly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly.
Selective cleavage of Tyr-|-Gly bond in picornavirus polyprotein.
NTP + H(2)O = NDP + phosphate
Biochemical function:
Biological process:
- not assigned
Cellular component:
Structure analysis Details
Assembly composition:
hetero 240-mer (preferred)
Assembly name:
ECHOVIRUS 11 COAT PROTEIN VP4 (preferred)
PDBe Complex ID:
PDB-CPX-185001 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
ECHOVIRUS 11 COAT PROTEIN VP1
Molecule details ›
Chain: A
Length: 292 amino acids
Theoretical weight: 32.79 KDa
Source organism: Echovirus E11
UniProt:
Structure domains: Jelly Rolls
Length: 292 amino acids
Theoretical weight: 32.79 KDa
Source organism: Echovirus E11
UniProt:
- Canonical:
Q8JKE8 (Residues: 570-861; Coverage: 13%)
Structure domains: Jelly Rolls
ECHOVIRUS 11 COAT PROTEIN VP2
Molecule details ›
Chain: B
Length: 262 amino acids
Theoretical weight: 29.05 KDa
Source organism: Echovirus E11
UniProt:
Structure domains: Jelly Rolls
Length: 262 amino acids
Theoretical weight: 29.05 KDa
Source organism: Echovirus E11
UniProt:
- Canonical: Q8JKE8 (Residues: 70-331; Coverage: 12%)
Structure domains: Jelly Rolls
ECHOVIRUS 11 COAT PROTEIN VP3
Molecule details ›
Chain: C
Length: 238 amino acids
Theoretical weight: 25.9 KDa
Source organism: Echovirus E11
UniProt:
Structure domains: Jelly Rolls
Length: 238 amino acids
Theoretical weight: 25.9 KDa
Source organism: Echovirus E11
UniProt:
- Canonical: Q8JKE8 (Residues: 332-569; Coverage: 11%)
Structure domains: Jelly Rolls
ECHOVIRUS 11 COAT PROTEIN VP4
Molecule details ›
Chain: D
Length: 68 amino acids
Theoretical weight: 7.38 KDa
Source organism: Echovirus E11
UniProt:
Structure domains: Picornavirus coat protein VP4
Length: 68 amino acids
Theoretical weight: 7.38 KDa
Source organism: Echovirus E11
UniProt:
- Canonical: Q8JKE8 (Residues: 2-69; Coverage: 3%)
Structure domains: Picornavirus coat protein VP4
