› 1h76

X-ray diffraction
2.15Å resolution

The crystal structure of diferric porcine serum transferrin

Released:
DOI: 10.2210/pdb1h76/pdb
PDB 1h76 coloured by chain and viewed from the front.
PDB 1h76 coloured by chain and viewed from the side.
PDB 1h76 coloured by chain and viewed from the top.
Source organism: Sus scrofa
Primary publication:
The crystal and molecular structures of diferric porcine and rabbit serum transferrins at resolutions of 2.15 and 2.60 A, respectively.
Hall DR, Hadden JM, Leonard GA, Bailey S, Neu M, Winn M, Lindley PF
Acta Crystallogr. D Biol. Crystallogr. 58 70-80 (2002)
PMID: 11752780

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serotransferrin Chain: A
Molecule details ›
Chain: A
Length: 696 amino acids
Theoretical weight: 77.07 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: P09571 (Residues: 1-696; Coverage: 100%)
Gene name: TF
Structure domains: Periplasmic binding protein-like II

Ligands and Environments

3 bound ligands:
Ligand CO3 2 x CO3
Ligand FE 2 x FE
Ligand NAG 1 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX9.5
Spacegroup: C2
Unit cell:
a: 223.77Å b: 44.89Å c: 78.86Å
α: 90° β: 105.39° γ: 90°
R-values:
R R work R free
0.136 0.136 0.182

Quick links

Citations

10 review citations

Biological Functions of the Secretome of Neisseria meningitidis.
Tommassen et al. (2017)
9 more

8 mentions without citation

Structural basis for iron piracy by pathogenic Neisseria.
Noinaj et al. (2012)
7 more