PDBe 1h6h

X-ray diffraction
1.7Å resolution

Structure of the PX domain from p40phox bound to phosphatidylinositol 3-phosphate


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Neutrophil cytosol factor 4 Chain: A
Molecule details ›
Chain: A
Length: 143 amino acids
Theoretical weight: 16.31 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q15080 (Residues: 2-144; Coverage: 42%)
Gene names: NCF4, SH3PXD4
Sequence domains: PX domain
Structure domains: Phox-like domain

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX9.6
Spacegroup: C2
Unit cell:
a: 96.76Å b: 33.642Å c: 76.43Å
α: 90° β: 132.42° γ: 90°
R R work R free
0.196 0.196 0.232
Expression system: Escherichia coli BL21(DE3)