1h53

X-ray diffraction
2Å resolution

Binding of Phosphate and Pyrophosphate ions at the active site of human Angiogenin as revealed by X-ray Crystallography

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Angiogenin Chain: A
Molecule details ›
Chain: A
Length: 123 amino acids
Theoretical weight: 14.08 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P03950 (Residues: 26-147; Coverage: 99%)
Gene names: ANG, RNASE5
Sequence domains: Pancreatic ribonuclease
Structure domains: Ribonuclease A-like domain

Ligands and Environments

2 bound ligands:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X13
Spacegroup: P21212
Unit cell:
a: 85.383Å b: 37.538Å c: 38.534Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.198 0.198 0.26
Expression system: Escherichia coli