1h4o

X-ray diffraction
1.95Å resolution

Monoclinic form of human peroxiredoxin 5

Released:

Function and Biology Details

Reaction catalysed:
2 R'-SH + ROOH = R'-S-S-R' + H(2)O + ROH
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peroxiredoxin-5, mitochondrial Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 161 amino acids
Theoretical weight: 16.92 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli M15
UniProt:
  • Canonical: P30044 (Residues: 54-214; Coverage: 75%)
Gene names: ACR1, PRDX5, SBBI10
Sequence domains: Redoxin
Structure domains: Glutaredoxin

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM30A
Spacegroup: P21
Unit cell:
a: 130.79Å b: 66.49Å c: 141.24Å
α: 90° β: 117.54° γ: 90°
R-values:
R R work R free
0.166 0.165 0.19
Expression system: Escherichia coli M15