X-ray diffraction
2Å resolution

Tyrosyl-tRNA synthetase from Thermus thermophilus complexed with tyrosinol


Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Tyrosine--tRNA ligase Chains: A, B
Molecule details ›
Chains: A, B
Length: 432 amino acids
Theoretical weight: 48.79 KDa
Source organism: Thermus thermophilus HB27
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P83453 (Residues: 1-432; Coverage: 100%)
Gene names: TT_C1033, tyrS
Sequence domains: tRNA synthetases class I (W and Y)
Structure domains:

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: P212121
Unit cell:
a: 67.794Å b: 111.05Å c: 141.226Å
α: 90° β: 90° γ: 90°
R R work R free
0.234 0.234 0.261
Expression system: Escherichia coli BL21(DE3)