1h1v

X-ray diffraction
2.99Å resolution

gelsolin G4-G6/actin complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Actin, alpha skeletal muscle Chain: A
Molecule details ›
Chain: A
Length: 375 amino acids
Theoretical weight: 41.86 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: P68135 (Residues: 3-377; Coverage: 100%)
Gene names: ACTA, ACTA1
Structure domains:
Gelsolin Chain: G
Molecule details ›
Chain: G
Length: 331 amino acids
Theoretical weight: 36.41 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P06396 (Residues: 439-769; Coverage: 44%)
Gene name: GSN
Structure domains: Severin

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: P212121
Unit cell:
a: 54.35Å b: 113.45Å c: 159.35Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.219 0.219 0.268
Expression system: Escherichia coli BL21