1h1i

X-ray diffraction
1.75Å resolution

CRYSTAL STRUCTURE OF QUERCETIN 2,3-DIOXYGENASE ANAEROBICALLY COMPLEXED WITH THE SUBSTRATE QUERCETN

Released:

Function and Biology Details

Reaction catalysed:
Quercetin + O(2) = 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoate + CO + H(+)
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Quercetin 2,3-dioxygenase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 350 amino acids
Theoretical weight: 37.96 KDa
Source organism: Aspergillus japonicus
Expression system: Aspergillus awamori
UniProt:
  • Canonical: Q7SIC2 (Residues: 1-350; Coverage: 100%)
Structure domains: Jelly Rolls

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: P21
Unit cell:
a: 109.298Å b: 55.745Å c: 124.163Å
α: 90° β: 98.39° γ: 90°
R-values:
R R work R free
0.15 0.148 0.183
Expression system: Aspergillus awamori