PDBe 1h1b

X-ray diffraction
2Å resolution

Function and Biology Details

Reaction catalysed:
Hydrolysis of proteins, including elastin. Preferential cleavage Val-|- > Ala-|-.
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
LEUKOCYTE ELASTASE Chains: A, B
Molecule details ›
Chains: A, B
Length: 218 amino acids
Theoretical weight: 23.32 KDa
Source organism: Homo sapiens
Structure domains: Trypsin-like serine proteases

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX9.6
Spacegroup: P4322
Unit cell:
a: 68.88Å b: 68.88Å c: 241.15Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.254 0.251 0.31