› 1gz9

X-ray diffraction
1.7Å resolution

High-Resolution Crystal Structure of Erythrina cristagalli Lectin in Complex with 2'-alpha-L-Fucosyllactose

Released:
DOI: 10.2210/pdb1gz9/pdb
PDB 1gz9 coloured by chain and viewed from the front.
PDB 1gz9 coloured by chain and viewed from the side.
PDB 1gz9 coloured by chain and viewed from the top.
Source organism: Erythrina crista-galli
Primary publication:
High-resolution crystal structures of Erythrina cristagalli lectin in complex with lactose and 2'-alpha-L-fucosyllactose and correlation with thermodynamic binding data.
Svensson C, Teneberg S, Nilsson CL, Kjellberg A, Schwarz FP, Sharon N, Krengel U
J. Mol. Biol. 321 69-83 (2002)
PMID: 12139934

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Lectin Chain: A
Molecule details ›
Chain: A
Length: 239 amino acids
Theoretical weight: 26.25 KDa
Source organism: Erythrina crista-galli
UniProt:
  • Canonical: P83410 (Residues: 1-239; Coverage: 100%)
Sequence domains: Legume lectin domain
Structure domains: Jelly Rolls

Ligands and Environments

Carbohydrate polymer : NEW Components: BGC, GAL, FUC
Carbohydrate polymer
2 bound ligands:
Ligand MN 1 x MN
Ligand CA 1 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MAX II BEAMLINE I711
Spacegroup: P43212
Unit cell:
a: 80.9Å b: 80.9Å c: 125.9Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.209 0.209 0.239

Quick links

Citations

2 review citations

Research advances and prospects of legume lectins.
Katoch et al. (2021)
1 more

4 mentions without citation

Legume Lectins: Proteins with Diverse Applications.
Lagarda-Diaz et al. (2017)
3 more