› 1gxl

X-ray diffraction
3Å resolution

SMC hinge domain from T. maritima with coiled coil

Released:
DOI: 10.2210/pdb1gxl/pdb
PDB entry 1gxl coloured by chain, front view.
PDB entry 1gxl coloured by chain, side view.
PDB entry 1gxl coloured by chain, top view.
Source organism: Thermotoga maritima
Primary publication:
Molecular architecture of SMC proteins and the yeast cohesin complex.
Haering CH, Löwe J, Hochwagen A, Nasmyth K
Mol Cell 9 773-88 (2002)
PMID: 11983169

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194737 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Chromosome partition protein Smc Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 213 amino acids
Theoretical weight: 24.26 KDa
Source organism: Thermotoga maritima
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9X0R4 (Residues: 473-685; Coverage: 18%)
Gene names: TM_1182, smc
Sequence domains: SMC proteins Flexible Hinge Domain
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: C2
Unit cell:
a: 136.4Å b: 115.5Å c: 68.96Å
α: 90° β: 93.7° γ: 90°
R-values:
R R work R free
0.252 0.252 0.301
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

131 review citations

Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair.
Symington LS. (2002)
130 more

17 mentions without citation

Towards a Unified Model of SMC Complex Function.
Hassler et al. (2018)
16 more