X-ray diffraction
1.7Å resolution

Apolipoprotein E4, 22k domain

Source organism: Homo sapiens
Entry authors: Verderame JR, Kantardjieff K, Segelke B, Weisgraber K, Rupp B

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Apolipoprotein E Chain: A
Molecule details ›
Chain: A
Length: 165 amino acids
Theoretical weight: 19.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
  • Canonical: P02649 (Residues: 19-183; Coverage: 55%)
Gene name: APOE
Sequence domains: Apolipoprotein A1/A4/E domain
Structure domains: Apolipoprotein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: P212121
Unit cell:
a: 45.511Å b: 53.089Å c: 73.372Å
α: 90° β: 90° γ: 90°
R R work R free
0.219 0.218 0.247
Expression system: Escherichia coli BL21