Assemblies
Assembly Name:
Isocitrate dehydrogenase [NADP]
Multimeric state:
homo dimer
Accessible surface area:
30515.13 Å2
Buried surface area:
7699.27 Å2
Dissociation area:
3,392.84
Å2
Dissociation energy (ΔGdiss):
52.55
kcal/mol
Dissociation entropy (TΔSdiss):
14.9
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-140025
Macromolecules
Chain: A
Length: 416 amino acids
Theoretical weight: 45.84 KDa
Source organism: Escherichia coli
Expression system: Not provided
UniProt:
Pfam: Isocitrate/isopropylmalate dehydrogenase
InterPro:
SCOP: Dimeric isocitrate & isopropylmalate dehydrogenases
Length: 416 amino acids
Theoretical weight: 45.84 KDa
Source organism: Escherichia coli
Expression system: Not provided
UniProt:
- Canonical:
P08200 (Residues: 1-416; Coverage: 100%)
Pfam: Isocitrate/isopropylmalate dehydrogenase
InterPro:
- Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic
- Isopropylmalate dehydrogenase-like domain
- Isocitrate/isopropylmalate dehydrogenase, conserved site
SCOP: Dimeric isocitrate & isopropylmalate dehydrogenases
![Isocitrate dehydrogenase [NADP] in PDB entry 1gro, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/1gro_entity_1_front_image-200x200.png "Homo dimeric assembly 1 of PDB entry <span class='highlight'>1gro</span> contains 2 copies of <span class='highlight'>Isocitrate dehydrogenase [NADP]</span>. Front view.")
![Isocitrate dehydrogenase [NADP] in PDB entry 1gro, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/1gro_entity_1_side_image-200x200.png "Homo dimeric assembly 1 of PDB entry <span class='highlight'>1gro</span> contains 2 copies of <span class='highlight'>Isocitrate dehydrogenase [NADP]</span>. Side view.")
![Isocitrate dehydrogenase [NADP] in PDB entry 1gro, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/1gro_entity_1_top_image-200x200.png "Homo dimeric assembly 1 of PDB entry <span class='highlight'>1gro</span> contains 2 copies of <span class='highlight'>Isocitrate dehydrogenase [NADP]</span>. Top view.")