› 1gjs

Solution NMR

Solution structure of the Albumin binding domain of Streptococcal Protein G

Released:
DOI: 10.2210/pdb1gjs/pdb
PDB entry 1gjs coloured by chain, ensemble of 30 models, front view.
PDB entry 1gjs coloured by chain, ensemble of 30 models, side view.
PDB entry 1gjs coloured by chain, ensemble of 30 models, top view.
Source organism: Streptococcus sp.
Primary publication:
Structure, specificity, and mode of interaction for bacterial albumin-binding modules.
Johansson MU, Frick IM, Nilsson H, Kraulis PJ, Hober S, Jonasson P, Linhult M, Nygren PA, Uhlén M, Björck L, Drakenberg T, Forsén S, Wikström M
J Biol Chem 277 8114-20 (2002)
PMID: 11751858

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148791 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Immunoglobulin G-binding protein G Chain: A
Molecule details ›
Chain: A
Length: 65 amino acids
Theoretical weight: 7.11 KDa
Source organism: Streptococcus sp.
Expression system: Escherichia coli
UniProt:
  • Canonical: P19909 (Residues: 246-299; Coverage: 10%)
Gene name: spg
Sequence domains: GA-like domain
Structure domains: Albumin-binding domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DISTANCE GEOMETRY AND RESTRAINED SIMULATED ANNEALING
Expression system: Escherichia coli

Quick links

Citations

5 review citations

Strategies to extend plasma half-lives of recombinant antibodies.
Kontermann RE. (2009)
4 more

8 mentions without citation

Mesothelin-Targeted Recombinant Immunotoxins for Solid Tumors.
Hagerty et al. (2020)
7 more