1ghq

X-ray diffraction
2.04Å resolution

CR2-C3D COMPLEX STRUCTURE

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Complement C3d fragment Chain: A
Molecule details ›
Chain: A
Length: 308 amino acids
Theoretical weight: 34.49 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P01024 (Residues: 996-1287, 1288-1300; Coverage: 19%)
Gene names: C3, CPAMD1
Structure domains: Glycosyltransferase
Complement receptor type 2 Chains: B, C
Molecule details ›
Chains: B, C
Length: 134 amino acids
Theoretical weight: 14.71 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P20023 (Residues: 21-153; Coverage: 13%)
Gene names: C3DR, CR2
Sequence domains: Sushi repeat (SCR repeat)
Structure domains: Complement Module, domain 1

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 14-BM-C
Spacegroup: R32
Unit cell:
a: 170Å b: 170Å c: 174Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.195 0.195 0.239