1gce

X-ray diffraction
1.8Å resolution

STRUCTURE OF THE BETA-LACTAMASE OF ENTEROBACTER CLOACAE GC1

Released:

Function and Biology Details

Reaction catalysed:
A beta-lactam + H(2)O = a substituted beta-amino acid
Biochemical function:
Biological process:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Beta-lactamase Chain: A
Molecule details ›
Chain: A
Length: 364 amino acids
Theoretical weight: 39.61 KDa
Source organism: Enterobacter cloacae
Expression system: Escherichia coli
UniProt:
  • Canonical: P05364 (Residues: 21-230, 231-381; Coverage: 100%)
Gene name: ampC
Sequence domains: Beta-lactamase
Structure domains: DD-peptidase/beta-lactamase superfamily

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: P21212
Unit cell:
a: 77.975Å b: 69.514Å c: 63.142Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.202 0.202 0.232
Expression system: Escherichia coli