1g8q

X-ray diffraction
1.6Å resolution

CRYSTAL STRUCTURE OF HUMAN CD81 EXTRACELLULAR DOMAIN, A RECEPTOR FOR HEPATITIS C VIRUS

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CD81 antigen Chains: A, B
Molecule details ›
Chains: A, B
Length: 90 amino acids
Theoretical weight: 9.92 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P60033 (Residues: 113-202; Coverage: 38%)
Gene names: CD81, TAPA1, TSPAN28
Structure domains: Tetraspanin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF
Spacegroup: P21
Unit cell:
a: 31.485Å b: 77.172Å c: 38.462Å
α: 90° β: 107.39° γ: 90°
R-values:
R R work R free
0.188 0.188 0.238
Expression system: Escherichia coli