1g5m

Solution NMR

HUMAN BCL-2, ISOFORM 1

Released:
Source organism: Homo sapiens
Primary publication:
Solution structure of the antiapoptotic protein bcl-2.
Proc Natl Acad Sci U S A 98 3012-7 (2001)
PMID: 11248023

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Apoptosis regulator Bcl-2 Chain: A
Molecule details ›
Chain: A
Length: 166 amino acids
Theoretical weight: 19.23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P10415 (Residues: 1-207; Coverage: 70%)
Gene name: BCL2
Sequence domains: Apoptosis regulator proteins, Bcl-2 family
Structure domains: Blc2-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli