› 1g26

Solution NMR

THE SOLUTION STRUCTURE OF A WELL-FOLDED PEPTIDE BASED ON THE 31-RESIDUE AMINO-TERMINAL SUBDOMAIN OF HUMAN GRANULIN A

Released:
DOI: 10.2210/pdb1g26/pdb
PDB entry 1g26 coloured by chain, ensemble of 10 models, front view.
PDB entry 1g26 coloured by chain, ensemble of 10 models, side view.
PDB entry 1g26 coloured by chain, ensemble of 10 models, top view.
Source organism: Homo sapiens
Primary publication:
Design and solution structure of a well-folded stack of two beta-hairpins based on the amino-terminal fragment of human granulin A.
Tolkatchev D, Ng A, Vranken W, Ni F
Biochemistry 39 2878-86 (2000)
PMID: 10715107

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151291 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Granulin-4 Chain: A
Molecule details ›
Chain: A
Length: 31 amino acids
Theoretical weight: 3.39 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P28799 (Residues: 281-311; Coverage: 5%)
Gene name: GRN
Sequence domains: Granulin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry and simulated annealing
Expression system: Not provided

Quick links

Citations

4 review citations

Progranulin (granulin-epithelin precursor, PC-cell-derived growth factor, acrogranin) mediates tissue repair and tumorigenesis.
He et al. (2003)
3 more

3 mentions without citation

Unexpected diversity in Shisa-like proteins suggests the importance of their roles as transmembrane adaptors.
Pei et al. (2012)
2 more