1frt

X-ray diffraction
4.5Å resolution

CRYSTAL STRUCTURE OF THE COMPLEX OF RAT NEONATAL FC RECEPTOR WITH FC

Released:
Source organism: Rattus norvegicus

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
IgG receptor FcRn large subunit p51 Chain: A
Molecule details ›
Chain: A
Length: 269 amino acids
Theoretical weight: 30.32 KDa
Source organism: Rattus norvegicus
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P13599 (Residues: 23-291; Coverage: 78%)
Gene names: Fcgrt, Fcrn
Sequence domains:
Beta-2-microglobulin Chain: B
Molecule details ›
Chain: B
Length: 99 amino acids
Theoretical weight: 11.65 KDa
Source organism: Rattus norvegicus
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P07151 (Residues: 21-119; Coverage: 100%)
Gene name: B2m
Sequence domains: Immunoglobulin C1-set domain
IGG FC Chain: C
Molecule details ›
Chain: C
Length: 205 amino acids
Theoretical weight: 23.42 KDa
Source organism: Rattus norvegicus
Expression system: Cricetulus griseus

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: I212121
Unit cell:
a: 125Å b: 145Å c: 216.5Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.423 0.423 not available
Expression system: Cricetulus griseus