› 1fib

X-ray diffraction
2.1Å resolution

RECOMBINANT HUMAN GAMMA-FIBRINOGEN CARBOXYL TERMINAL FRAGMENT (RESIDUES 143-411) BOUND TO CALCIUM AT PH 6.0

Released:
DOI: 10.2210/pdb1fib/pdb
PDB 1fib coloured by chain and viewed from the front.
PDB 1fib coloured by chain and viewed from the side.
PDB 1fib coloured by chain and viewed from the top.
Source organism: Homo sapiens
Primary publication:
Crystal structure of a 30 kDa C-terminal fragment from the gamma chain of human fibrinogen.
Yee VC, Pratt KP, Côté HC, Trong IL, Chung DW, Davie EW, Stenkamp RE, Teller DC
Structure 5 125-38 (1997)
PMID: 9016719

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fibrinogen gamma chain Chain: A
Molecule details ›
Chain: A
Length: 269 amino acids
Theoretical weight: 30.24 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
  • Canonical: P02679 (Residues: 169-433; Coverage: 62%)
  • Best match: P02679-2 (Residues: 169-437)
Gene names: FGG, PRO2061
Sequence domains: Fibrinogen beta and gamma chains, C-terminal globular domain
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand CA 1 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P21
Unit cell:
a: 37.53Å b: 68.42Å c: 47.67Å
α: 90° β: 105.36° γ: 90°
R-values:
R R work R free
0.159 0.159 0.227
Expression system: Komagataella pastoris

Quick links

Citations

18 review citations

Fibrin Formation, Structure and Properties.
Weisel et al. (2017)
17 more