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LIPOXYGENASE-1 (SOYBEAN) AT 100K, Q697E MUTANT

Source organism: Glycine max
Biochemical function: linolenate 9R-lipoxygenase activity
Biological process: lipid oxidation
Cellular component: cytoplasm

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EC 1.13.11.12: Linoleate 13S-lipoxygenase

Reaction catalysed:
Alpha-linolenate + O(2) = (9Z,11E,13S,15Z)-13-hydroperoxyoctadeca-9,11,15-trienoate
Systematic name:
Linoleate:oxygen 13-oxidoreductase
Alternative Name(s):
  • 13-lipoperoxidase
  • 13-lipoxidase
  • 13-lipoxidase
  • Carotene oxidase
  • Fat oxidase
  • Lionoleate:O(2) 13-oxidoreductase
  • Lipoperoxidase
  • Lipoxidase
  • Lipoxidase

GO terms

Sequence families

Pfam Protein families (Pfam)
PF00305
Domain description: Lipoxygenase
Occurring in:
  1. Seed linoleate 13S-lipoxygenase-1
The deposited structure of PDB entry 1fgr contains 1 copy of Pfam domain PF00305 (Lipoxygenase) in Seed linoleate 13S-lipoxygenase-1. Showing 1 copy in chain A.

PF01477
Domain description: PLAT/LH2 domain
Occurring in:
  1. Seed linoleate 13S-lipoxygenase-1
The deposited structure of PDB entry 1fgr contains 1 copy of Pfam domain PF01477 (PLAT/LH2 domain) in Seed linoleate 13S-lipoxygenase-1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001246
Domain description: Lipoxygenase, plant
Occurring in:
  1. Seed linoleate 13S-lipoxygenase-1
IPR013819
Domain description: Lipoxygenase, C-terminal
Occurring in:
  1. Seed linoleate 13S-lipoxygenase-1
IPR001024
Domain description: PLAT/LH2 domain
Occurring in:
  1. Seed linoleate 13S-lipoxygenase-1
IPR020834
Domain description: Lipoxygenase, conserved site
Occurring in:
  1. Seed linoleate 13S-lipoxygenase-1
IPR020833
Domain description: Lipoxygenase, iron binding site
Occurring in:
  1. Seed linoleate 13S-lipoxygenase-1
IPR027433
Domain description: Lipoxygenase, domain 3
Occurring in:
  1. Seed linoleate 13S-lipoxygenase-1
IPR036226
Domain description: Lipoxigenase, C-terminal domain superfamily
Occurring in:
  1. Seed linoleate 13S-lipoxygenase-1
IPR042057
Domain description: Plant lipoxygenase, PLAT/LH2 domain
Occurring in:
  1. Seed linoleate 13S-lipoxygenase-1
IPR000907
Domain description: Lipoxygenase
Occurring in:
  1. Seed linoleate 13S-lipoxygenase-1
IPR036392
Domain description: PLAT/LH2 domain superfamily
Occurring in:
  1. Seed linoleate 13S-lipoxygenase-1

Structure domains

CATH CATH domains
1.20.245.10
Class: Mainly Alpha
Architecture: Up-down Bundle
Topology: Lipoxygenase-1; domain 5
Homology: Lipoxygenase-1; Domain 5
Occurring in:
  1. Seed linoleate 13S-lipoxygenase-1
The deposited structure of PDB entry 1fgr contains 1 copy of CATH domain 1.20.245.10 (Lipoxygenase-1; domain 5) in Seed linoleate 13S-lipoxygenase-1. Showing 1 copy in chain A.
3.10.450.60
Class: Alpha Beta
Architecture: Roll
Topology: Nuclear Transport Factor 2; Chain: A,
Homology: Nuclear Transport Factor 2; Chain: A,
Occurring in:
  1. Seed linoleate 13S-lipoxygenase-1
The deposited structure of PDB entry 1fgr contains 1 copy of CATH domain 3.10.450.60 (Nuclear Transport Factor 2; Chain: A,) in Seed linoleate 13S-lipoxygenase-1. Showing 1 copy in chain A.
4.10.372.10
Class: Few Secondary Structures
Architecture: Irregular
Topology: Lipoxygenase-1; domain 3
Homology: Lipoxygenase-1; Domain 3
Occurring in:
  1. Seed linoleate 13S-lipoxygenase-1
The deposited structure of PDB entry 1fgr contains 1 copy of CATH domain 4.10.372.10 (Lipoxygenase-1; domain 3) in Seed linoleate 13S-lipoxygenase-1. Showing 1 copy in chain A.
4.10.375.10
Class: Few Secondary Structures
Architecture: Irregular
Topology: Lipoxygenase-1; domain 2
Homology: Lipoxygenase-1; Domain 2
Occurring in:
  1. Seed linoleate 13S-lipoxygenase-1
The deposited structure of PDB entry 1fgr contains 1 copy of CATH domain 4.10.375.10 (Lipoxygenase-1; domain 2) in Seed linoleate 13S-lipoxygenase-1. Showing 1 copy in chain A.
2.60.60.20
Class: Mainly Beta
Architecture: Sandwich
Topology: Lipoxygenase-1
Homology: PLAT/LH2 domain
Occurring in:
  1. Seed linoleate 13S-lipoxygenase-1
The deposited structure of PDB entry 1fgr contains 1 copy of CATH domain 2.60.60.20 (Lipoxygenase-1) in Seed linoleate 13S-lipoxygenase-1. Showing 1 copy in chain A.
SCOP SCOP annotations
48485
Class: All alpha proteins
Fold: Lipoxigenase
Superfamily: Lipoxigenase
Occurring in:
  1. Seed linoleate 13S-lipoxygenase-1
The deposited structure of PDB entry 1fgr contains 1 copy of SCOP domain 48485 (Plant lipoxigenases) in Seed linoleate 13S-lipoxygenase-1. Showing 1 copy in chain A.
49724
Class: All beta proteins
Fold: Lipase/lipooxygenase domain (PLAT/LH2 domain)
Superfamily: Lipase/lipooxygenase domain (PLAT/LH2 domain)
Occurring in:
  1. Seed linoleate 13S-lipoxygenase-1
The deposited structure of PDB entry 1fgr contains 1 copy of SCOP domain 49724 (Lipoxigenase N-terminal domain) in Seed linoleate 13S-lipoxygenase-1. Showing 1 copy in chain A.

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