› 1fge

Solution NMR

EPIDERMAL GROWTH FACTOR (EGF) SUBDOMAIN OF HUMAN THROMBOMODULIN (NMR, 14 STRUCTURES)

Released:
DOI: 10.2210/pdb1fge/pdb
PDB entry 1fge coloured by chain, ensemble of 14 models, front view.
PDB entry 1fge coloured by chain, ensemble of 14 models, side view.
PDB entry 1fge coloured by chain, ensemble of 14 models, top view.
Source organism: Homo sapiens
Primary publication:
Structural resiliency of an EGF-like subdomain bound to its target protein, thrombin.
Hrabal R, Komives EA, Ni F
Protein Sci 5 195-203 (1996)
PMID: 8745396

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139431 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thrombomodulin Chain: A
Molecule details ›
Chain: A
Length: 20 amino acids
Theoretical weight: 2.22 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P07204 (Residues: 425-444; Coverage: 4%)
Gene names: THBD, THRM
Sequence domains: Complement Clr-like EGF-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Not provided

Quick links

Citations

1 review citation

Thrombomodulin: from haemostasis to inflammation and tumourigenesis.
Koutsi et al. (2008)
11 other articles

1 mention without citation

The dipeptidyl peptidase IV inhibitors vildagliptin and K-579 inhibit a phospholipase C: a case of promiscuous scaffolds in proteins.
Chakraborty et al. (2013)